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    -2017-
  1. Yoshiki Yasukochi, Jun Sakuma, Ichiro Takeuchi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Yoshiji Yamada.
    Longitudinal exome-wide association study to identify genetic susceptibility loci for hypertension in a Japanese population.
    Exp Mol Med 2017;49:e409.

  2. Chikara Ueyama, Hideki Horibe, Yuichiro Yamase, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Yoshiji Yamada.
    Associations of smoking with the prevalence of common complex diseases and metabolic parameters in community-dwelling Japanese individuals.
    Biomed Rep 2017;7:429-438

  3. Kumpei Tanisawa, Nobuyoshi Hirose, Yasumichi Arai, Hiroshi Shimokata, Yoshiji Yamada, Hisashi Kawai, Motonaga Kojima, Shuichi Obuchi, Hirohiko Hirano, Hiroyuki Suzuki, Yoshinori Fujiwara, Kazushige Ihara, Yu Taniguchi, Shoji Shinkai, Maki Sugaya, Mitsuru Higuchi, Tomio Arai, Seijiro Mori, Motoji Sawabe, Noriko Sato, Masaaki Muramatsu, Masashi Tanaka.
    Inverse association between height-increasing alleles and extreme longevity in Japanese women.
    J Gerontol A Biol Sci Med Sci 2018;73:588-595.

  4. Yoshiki Yasukochi, Jun Sakuma, Ichiro Takeuchi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Yoshiji Yamada.
    Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
    Mol Genet Genomics 2018;293:371-379.

  5. Yoshiji Yamada, Hideki Horibe, Mitsutoshi Oguri, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Motoji Sawabe.
    Identification of novel hyper- and hypo-methylated CpG sites and genes associated with atherosclerotic plaque using an epigenome-wide association study.
    Int J Mol Med 2018;41:2724-2732.

  6. Yoshiji Yamada, Ichiro Takeuchi, Koji Tsuda, Noboru Kunihiro, Jun Sakuma.
    Genetic epidemiology of cardiovascular disease and its application to personalized prevention.
    Fundamentals and Applications of Predictive, Preventive and Personalized Medicine. Moscow, 2017 (in press)

  7. Yoshiji Yamada, Yoshiki Yasucochi.
    Genetics of coronary artery disease.
    In Dhavendra Kumar, Perry Elliot, eds. Principle and Practice of Clinical Cardiovascular Genetics. New York: Oxford University Press; 2017 (in press)

  8. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of five genetic variants as novel determinants of type 2 diabetes mellitus in Japanese individuals by exome-wide association studies.
    Oncotarget 2017;8:80492-80505.

  9. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of TNFSF13, SPATC1L, SLC22A25, and SALL4 as novel susceptibility loci for atrial fibrillation in Japanese individuals by an exome-wide association study.
    Mol Med Rep 2017;16:5823-5832.

  10. Sariya Dechamethakun, Noriko Sato, Shinobu Ikeda, Motoji Sawabe, Seijiro Mori, Yoshiji Yamada, Masashi Tanaka, Masaaki Muramatsu, Tomio Arai.
    Association of Macrophage Capping Protein (CAPG) Arg335His Polymorphism and Cancer Susceptibility in the Elderly Japanese.
    J Gerontol Geriatr Res 2017;6:1000417.

  11. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of polymorphisms in 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association studies.
    Oncotarget 2017;8:43068-43079.

  12. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of eight genetic variants as novel determinants for dyslipidemia in Japanese by exome-wide association studies.
    Oncotarget 2017;8:38950-38961.

  13. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of STXBP2 as a novel susceptibility locus for myocardial infarction in Japanese individuals by an exome-wide association study.
    Oncotarget 2017;8:33527-33535.

  14. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of C21orf59 and ATG2A as novel determinants of renal function-related traits in Japanese by exome-wide association studies.
    Oncotarget 2017;8:45259-45273.

  15. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of rs7350481 at chromosome 11q23.3 as a novel determinant of metabolic syndrome in Japanese individuals by exome-wide association studies.
    Oncotarget 2017;8:39296-39308.

  16. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of EGFLAM, SPATC1L, and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.
    Int J Mol Med 2017;39:1091-1100.

  17. Yoshiji Yamada, Jun Sakuma, Ichiro Takeuchi, Yoshiki Yasukochi, Kimihiko Kato, Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Masaaki Muramatsu, Motoji Sawabe, Yoshinori Fujiwara, Yu Taniguchi, Shuichi Obuchi, Hisashi Kawai, Shoji Shinkai, Seijiro Mori, Tomio Arai, Masashi Tanaka.
    Identification of six polymorphisms as novel susceptibility loci for ischemic or hemorrhagic stroke by exome-wide association studies.
    Int J Mol Med 2017;39:1477-1491.

  18. Takuya Sumi, Mitsutishi Oguri, Tetsuo Fujimaki, Hideki Horibe, Kimihiko Kato, Kota Matsui, Ichiro Takeuchi, Toyoaki Murohara, Yoshiji Yamada.
    Association of renal function with clinical parameters and conditions in a longitudinal population-based epidemiological stidy.
    Biomed Rep 2017;6:242-250.

  19. John M. Gregson, Daniel Freitag, Praveen Surendran, Nathan O. Stitziel, Rajiv Chowdhury, Stephen Burgess, Stephen Kaptoge, Pei Gao, James R. Staley, Peter Willeit, Sune Nielsen, Muriel Caslake, Stella Trompet, Linda M. Polfus, Kari Kuulasmaa, Jukka Kontto, Markus Perola, Stefan Blankenberg, Giovanni Veronesi, Francesco Gianfagna, Satu Mannisto, Akinori Kimura, Honghuang Lin, Dermot F. Reilly, Mathias Gorski, Vladan Mijatovic; CKDGen consortium, Patricia Munroe, Georg Ehret; International Consortium for Blood Pressure, Alex Thompson, Maria Uria-Nickelsen, Anders Malarstig, Abbas Dehghan; CHARGE inflammation working group, Thomas F. Vogt, Taishi Sasaoka, Fumihiko Takeuchi, Norihiro Kato, Yoshiji Yamada, Frank Kee Martina Muller-Nurasyid, Jean Ferrieres, Dominique Arveiler, Philippe Amouyel, Veikko Salomaa, Eric Boerwinkle, Simon G. Thompson, Ian Ford, J. Wouter Jukema, Naveed Sattar, Chris Packard, Abdulla al Shafi Majumder, Dewan S. Alam, Panos Deloukas, Heribert Schunkert, Nilesh Samani, Sekar Kathiresan; MICAD Exome consortium, Borge G. Nordestgaard, Danish Saleheen, Joanna M. M. Howson, Emanuele Di Angelantonio, Adam Butterworth, John Danesh; EPIC-CVD consortium and the CHD Exome+ consortium.
    Genetic invalidation of Lp-PLA2 as a therapeutic target: large-scale study of five functional Lp-PLA2 lowering alleles.
    Eur J Prev Cardiol 2017;24:492-504.

    20. -2016-
  20. Mitsutoshi Oguri, Tetsuo Fujimaki, Hideki Horibe, Kimihiko Kato, Kota Matsui, Ichiro Takeuchi, Yoshiji Yamada.
    Obesity-related changes in clinical parameters and conditions in a longitudinal population-based epidemiological study.
    Obes Res Clin Pract 2017;11:299-314.

  21. Saeko Tada-Oikawa, Gaku Ichihara, Hitomi Fukatsu, Yuka Shimanuki, Natsuki Tanaka, Yuka Suzuki, Masahiko Murakami, Kiyora Izuoka, Jie Chang, Wenting Wu, Yoshiji Yamada, Sahoko Ichihara.
    Titanium dioxide particle type and concentration influence the inflammatory response in a model of human intestinal tract.
    Int J Mol Sci 2016;17:576.

  22. Tamotsu Nishida, Yoshiji Yamada.
    SUMOylation of the KRAB zinc-finger transcription factor PARIS/ZNF746 regulates its transcriptional activity.
    Biochem Bioiphys Res Commun 2016;473:1261-1267.

  23. Kumpei Tanisawa, Yasumichi Arai, Nobuyoshi Hirose, Hiroshi Shimokata, Yoshiji Yamada, Hisashi Kawai, Motonaga Kojima, Shuichi Obuchi, Hirohiko Hirano, Hideyo Yoshida, Hiroyuki Suzuki, Yoshinori Fujiwara, Kazushige Ihara, Maki Sugaya, Tomio Arai, Seijiro Mori, Motoji Sawabe, Noriko Sato, Masaaki Muramatsu, Mitsuru Higuchi, Yao-Wen Liu, Qing-Peng Kong, Masashi Tanaka.
    Exome-wide association study identifies CLEC3B missense variant p.S106G as being associated with extreme longevity in East Asian populations.
    J Gerontol A Biol Sci Med Sci 2017;72:309-318.

  24. Yuichiro Yamase, Kimihiko Kato, Hideki Horibe, Chikara Ueyama, Tetsuo Fujimaki, Mitsutoshi Oguri, Masazumi Arai, Sachiro Watanabe, Toyoaki Murohara, Yoshiji Yamada.
    Association of genetic variants with atrial fibrillation.
    Biomed Rep 2016;4:178-182.

  25. Traylor M, Zhang CR, Adib-Samii P, Devan WJ, Parsons OE, Lanfranconi S, Gregory S, Cloonan L, Falcone GJ, Radmanesh F, Fitzpatrick K, Kanakis A, Barrick TR, Moynihan B, Lewis CM, Boncoraglio GB, Lemmens R, Thijs V, Sudlow C, Wardlaw J, Rothwell PM, Meschia JF, Worrall BB, Levi C, Bevan S, Furie KL, Dichgans M, Rosand J, Markus HS, Rost N, Smoller S, Sorkin J, Wang X, Selim M, Pikula A, Wolf P, Debette S, Seshadri S, de Bakker P, Chasman D, Rexrode K, Chen I, Rotter J, Luke M, Sale M, Lee TH, Chang KC, Elkind M, Goldstein L, James ML, Breteler M, O'Donnell C, Leys D, Carty C, Kidwell C, Olesen J, Sharma P, Rich S, Tatlisumak T, Happola O, Bijlenga P, Soriano C, Giralt E, Roquer J, Jimenez-Conde J, Cotlarcius I, Hardy J, Korostynski M, Boncoraglio G, Ballabio E, Parati E, Mateusz A, Urbanik A, Dziedzic T, Jagiella J, Gasowski J, Wnuk M, Olszanecki R, Pera J, Slowik A, Juchniewicz KJ, Levi C, Nyquist P, Cendes I, Cabral N, Franca P, Goncalves A, Keller L, Crisby M, Kostulas K, Lemmens R, Ahmadi K, Opherk C, Duering M, Dichgans M, Malik R, Gonik M, Staals J, Melander O, Burri P, Sadr-Nabavi A, Romero J, Biffi A, Anderson C, Falcone G, Brouwers B, Rosand J, Rost N, Du R, Kourkoulis C, Battey T, Lubitz S, Mueller-Myhsok B, Meschia J, Brott T, Pare G, Pichler A, Enzinger C, Schmidt H, Schmidt R, Seiler S, Blanton S, Yamada Y, Bersano A, Rundek T, Sacco R, Yvonne Chan YF, Gschwendtner A, Deng Z, Barr T, Gwinn K, Corriveau R, Singleton A, Waddy S, Launer L, Chen C, Le KE, Lee WL, Tan EK, Olugbodi A, Rothwell P, Schilling S, Mok V, Lebedeva E, Jern C, Jood K, Olsson S, Kim H, Lee C, Kilarski L, Markus H, Peycke J, Bevan S, Sheu W, Chiou HY, Chern J, Giraldo E, Taqi M, Jain V, Lam O, Howard G, Woo D, Kittner S, Mitchell B, Cole J, O'Connell J, Milewicz D, Illoh K, Worrall B, Stine C, Karaszewski B, Werring D, Sofat R, Smalley J, Lindgren A, Hansen B, Norrving B, Smith G, Martin JJ, Thijs V, Klijn K, Van't Hof F, Algra A, Macleod M, Perry R, Arnett D, Pezzini A, Padovani A, Cramer S, Fisher M, Saleheen D, Broderick J, Kissela B, Doney A, Sudlow C, Rannikmae K, Silliman S, McDonough C, Walters M, Pedersen A, Nakagawa K, Chang C, Dobbins M, McArdle P, Chang YC, Brown R, Brown D, Holliday E, Kalaria R, Maguire J, Attia J, Farrall M, Giese AK, Fornage M, Majersik J, Cushman M, Keene K, Bennett S, Tirschwell D, Psaty B, Reiner A, Longstreth W, Spence D, Montaner J, Fernandez-Cadenas I, Langefeld C, Bushnell C, Heitsch L, Lee JM, Sheth K.
    Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.
    Neurology 2016;86:146-153.

    26. -2015-
  26. Tada-Oikawa S, Ichihara G, Suzuki Y, Izuoka K, Yamada Y, Mishima T, Ichihara S.
    Zn(II) released from zinc oxide nano/micro particles suppresses vasculogenesis in human endothelial colony-forming cells.
    Toxicol Rep 2015;2:692-701.

  27. Wen-jie Lu, Yoshiji Yamada, Jun Sakuma.
    Privacy-preserving genome-wide association studies on cloud environment using fully homomorphic encryption.
    BMC Med Inform Decis Mak 2015;15(Suppl 5):S1.

  28. Maria Studneva, Mark Mandrik, Sihong Song, Evgeniya Tretyak, Ivan Krasnyuk, Yoshiji Yamada, Aleksandr Tukavin, Afaf Ansari, Ivan Kozlov, Chris Reading, Yinfa Ma, Kurt Krapfenbauer, Andrey Svistunov, Sergey Suchkov.
    Strategic aspects of higher education reform to cultivate specialists in diagnostic and biopharma industry as applicable to Predictive, Preventive and Personalized Medicine as the Medicine of the Future.
    EPMA J 2015;6:18.

  29. Heying Zhou, Seijiro Mori, Tatsuro Ishizaki, Masashi Tanaka, Kumpei Tanisawa, Makiko Naka-Mieno, Motoji Sawabe, Tomio Arai, Masaaki Muramatsu, Yoshiji Yamada, Hideki Ito.
    Genetic risk score based on the lifetime prevalence of femoral fracture in 924 consecutive autopsies of Japanese males.
    J Bone Miner Metab 2016;34:685-691.

  30. Daisuke Nishizawa, Shinya Kasai, Junko Hasegawa, Naomi Sato, Hidetaka Yamada, Fumihiko Tanioka, Makoto Nagashima, Ryoji Katoh, Yasuo Satoh, Megumi Tagami, Hiroshi Ujike, Norio Ozaki, Toshiya Inada, Nakao Iwata, Ichiro Sora, Masaomi Iyo, Mitsuhiko Yamada, Naoki Kondo, Moo-Jun Won, Nobuya Naruse, Kumi Uehara-Aoyama, Masanari Itokawa, Kazutaka Ohi, Ryota Hashimoto, Kumpei Tanisawa, Tomio Arai, Seijiro Mori, Motoji Sawabe, Makiko Naka-Mieno, Yoshiji Yamada, Miki Yamada, Noriko Sato, Masaaki Muramatsu, Masashi Tanaka, Yoko Irukayama-Tomobe, Yuki C Sato, Takeshi Sakurai, Masakazu Hayashida, Haruhiko Sugimura, Kazutaka Ikeda.
    Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies.
    Mol Brain 2015;8:50.

  31. Wenjie Lu, Yoshiji Yamada, Jun Sakuma.
    Efficient secure outsourcing of genome-wide association studies.
    Proceedings of IEEE Security and Privacy Workshop May 21, 2015, p3-6

  32. David A. duVerle, Shohei Kawasaki, Yoshiji Yamada, Jun Sakuma, Koji Tsuda.
    Privacy-preserving statistical analysis by exact logistic regression.
    Proceedings of IEEE Security and Privacy Workshop May 21, 2015, p7-16

  33. Yoshiko Murakata, Tetsuo Fujimaki, Yoshiji Yamada.
    Age-related changes in clinical parameters and their relations to common complex diseases.
    Biomed Rep 2015;3:767-777.

  34. Chikara Ueyama, Hideki Horibe, Yuichiro Yamase, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Masazumi Arai, Sachiro Watanabe, Toyoaki Murohara, Yoshiji Yamada.
    Association of polymorphisms of FURIN and ZPR1 with metabolic syndrome.
    Biomed Rep 2015;3:641-647.

  35. Yuichiro Yamase, Hideki Horibe, Chikara Ueyama, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Masazumi Arai, Sachiro Watanabe, Yoshiji Yamada.
    Association of polymorphisms of TOMM40 and SLC22A4 with ischemic stroke.
    Biomed Rep 2015;3:491-498.

  36. Yoshiji Yamada.
    Molecular genetics of coronary artery disease and ischemic stroke.
    Personalized Medicine Universe 2015;4:4-12.

  37. Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Tetsuo Fujimaki.
    Association of genetic variants with dyslipidemia and chronic kidney disease in a longitudinal population-based genetic epidemiological study.
    Int J Mol Med 2015;35:1290-1300.

  38. Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Tetsuo Fujimaki.
    Association of genetic variants with coronary artery disease and ischemic stroke in a longitudinal population-based genetic epidemiological study.
    Biomed Rep 2015;3:413-419.

  39. Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Mitsutoshi Oguri, Tetsuo Fujimaki.
    Association of genetic variants of the alpha-kinase 1 gene with type 2 diabetes mellitus in a longitudinal population-based genetic epidemiological study.
    Biomed Rep 2015;3:347-354.

  40. Yoshiji Yamada, Kota Matsui, Ichiro Takeuchi, Mitsutoshi Oguri, Tetsuo Fujimaki.
    Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study.
    Int J Mol Med 2015;35:1189-1198.

  41. Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Reiko Matsuoka, Shintaro Abe, Fumitaka Tokoro, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Yoshiji Yamada.
    Association of a polymorphism of the interleukin 6 receptor gene with chronic kidney disease in Japanese individuals.
    Nephrology 2015;20:273-278.

  42. Shintaro Abe, Fumitaka Tokoro, Reiko Matsuoka, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Shinya Minatoguchi, Yoshiji Yamada.
    Association of genetic variants with dyslipidemia.
    Mol Med Rep 2015;12:5429-5436.

  43. Reiko Matsuoka, Shintaro Abe, Fumitaka Tokoro, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Shinya Minatoguchi, Yoshiji Yamada.
    Association of six genetic variants with myocardial infarction.
    Int J Mol Med 2015;35:1451-1459.

  44. Fumitaka Tokoro, Reiko Matsuoka, Shintaro Abe, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Shinya Minatoguchi, Yoshiji Yamada.
    Association of a genetic variant of the ZPR1 zinc finger gene (ZPR1) with type 2 diabetes mellitus in Japanese individuals.
    Biomed Rep 2015;3:88-92.

  45. Tetsuo Fujimaki, Mitsutoshi Oguri, Hideki Horibe, Kimihiko Kato, Reiko Matsuoka, Shintaro Abe, Fumitaka Tokoro, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Yoshiji Yamada.
    Association of a transcription factor 21 gene polymorphism with hypertension.
    Biomed Rep 2015:3:118-122.

  46. Yamada Y.
    Genetics and genomics of osteoporosis and related disorders.
    In Dhavendra Kumar, Charis Eng, eds. Genomics Medicine: Priciple and Practice,Second Edition.
    New York: Oxford University Press;P352-368,2015.

  47. Miki Yamada, Noriko Sato, Shinobu Ikeda, Tomio Arai, Motoji Sawabe, Seijiro Mori, Yoshiji Yamada, Masaaki Muramatsu, Masashi Tanaka.
    Association of the chromodomain helicase DNA-binding protein 4 (CHD4) missense variation p.D140E with cancer: potential interaction with smoking.
    Genes Chromosomes Cancer 2015;54:122-128.

  48. Heying Zhou, Seijiro Mori, Masashi Tanaka, Motoji Sawabe, Tomio Arai, Masaaki Muramatsu, Makiko Naka-Mieno, Shoji Shinkai, Yoshiji Yamada, Motohiko Miyachi, Haruka Murakami, Kiyoshi Sanada, Hideki Ito.
    A missense single nucleotide polymorphism, V114I of the Werner syndrome gene, is associated with the risk of osteoporosis and femoral fracture in the Japanese population.
    J Bone Miner Metab 2015;33:694-700.

    49. -2014-
  49. Ziad A Ali, Vinicio de Jesus Perez, Ke Yuan, Mark Orcholski, Stephen Pan, Wei Qi, Gaurav Chopra, Christopher Adams, Yoko Kojima, Nicholas J Leeper, Xiumei Qu, Kathia Zaleta-Rivera, Kimihiko Kato, Yoshiji Yamada, Mitsutoshi Oguri, Allan Kuchinsky, Stanley L Hazen, J Wouter Jukema, Santhi K Ganesh, Elizabeth G Nabel, Keith Channon, Martin B Leon, Alain Charest, Thomas Quertermous, Euan A Ashley.
    Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.
    J Clin Invest 2014;124:5159-5174.

  50. Yoshiko Murakata, Tetsuo Fujimaki, Yoshiji Yamada.
    Association of a butyrophilin, subfamily 2, member A1 gene polymorphism with hypertension.
    Biomed Rep 2014;2:818-822.

  51. Horibe H, Ueyama C, Fujimaki T, Oguri M, Kato K, Ichihara S, Yamada Y.
    Association of a polymorphism of BTN2A1 with dislipidemia in community-dwelling individuals.
    Mol Med Rep 2014;9:808-812.

  52. Fujimaki T, Horibe H, Oguri M, Kato K, Yamada Y.
    Association of genetic variants of the ƒΏ-kinase 1 gene with myocardial infarction in community-dwelling individuals.
    Biomed Rep 2014;2:127-31.

  53. Chang J, Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Kato C, Yamada Y, Ichihara G, Kato M, Ichihara S.
    Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat.
    Diabetol Metab Syndr 2014;6:8.

  54. Pereira TV, Kimura L, Suwazono Y, Nakagawa H, Daimon M, Oizumi T, Kayama T, Kato T, Li L, Chen S, Gu D, Renner W, Marz W, Yamada Y, Bagos PG, Mingroni-Netto RC.
    Multivariate meta-analysis of the association of G-protein beta 3 gene (GNB3) haplotypes with cardiovascular phenotypes.
    Mol Biol Rep 2014;41:3113-3125.

  55. Yamada Y, Nishida T, Horibe H, Oguri M, Kato K, Sawabe M.
    Identification of hypo- and hypermethylated genes related to atherosclerosis by a genome-wide analysis of DNA methylation.
    Int J Mol Med 2014;33:1355-1363.

    56. -2013
  56. Yamada Y, Nishida T, Ichihara S, Kato K, Fujimaki T, Oguri M, Horibe H, Watanabe S, Satoh K, Aoyagi Y, Fukuda M, Sawabe M.
    Identification of 3q28 and ALPK1 as susceptibility loci for chronic kidney disease in Japanese individuals by a genome-wide association study.
    J Med Genet 2013;50:410-418.

  57. Yamaguchi T, Kitamori K, Ichihara G, Suzuki Y, Ochiai M, Yamada Y, Tada-Oikawa S, Tsuchikura S, Yamori Y, Ichihara S.
    Serial changes in adipocytokines and cardiac function in a rat model of the metabolic syndrome.
    Clin Exp Pharmacol Physiol 2013;40:443-448.

  58. Suzuki Y, Ichihara G, Sahabudeen SM, Kato A, Yamaguchi T, Imanaka-Yoshida K, Yoshida T, Yamada Y, Ichihara S.
    Rats with metabolic syndrome resist the protective effects of N-acetyll-cystein against impaired spermatogenesis induced by high-phosphorus/zinc-free diet.
    Exp Toxicol Pathol 2013;65:1173-1182.

  59. Ueyama C, Horibe H, Fujimaki T, Oguri M, Kato K, Yamada Y.
    Association of genetic variants of CELSR1 and 3q28 with hypertension in community-dwelling individuals.
    Biomed Rep 2013;1:840-844.

  60. Shimokata S, Oguri M, Fujimaki T, Horibe H, Kato K, Yamada Y.
    Association between polymorphisms of the ƒΏ-kinase 1 gene and type 2 diabetes mellitus in community-dwelling individuals.
    Biomed Rep 2013;1:940-944.

  61. Oguri M, Fujimaki T, Horibe H, Kato K, Ichihara S, Yamada Y.
    Association of a polymorphism of BTN2A1 with chronic kidney disease in community-dwelling individuals.
    Biomed Rep 2013;1:868-872.

    62. -2012-
  62. Kato K, Tokuda Y, Inagaki N, Yoshida T, Fujimaki T, Oguri M, Hibino T, Yokoi K, Murohara T, Yamada Y.
    Association of a polymorphism of the matrix metallopeptidase gene with long-term outcome of thoracic aortic aneurysm.
    Int J Mol Med 2012;29:125-132.

  63. Clarke R, Bennett D, Parish S, Verhoef P, Dotsch-Klerk M, Lathrop M, Xu P, Nordestgaard BG, Holm H, Hopewell JC, Saleheen D, Tanaka T, Anand SS, Chambers J, Kleber MK, Ouwehand WH, Yamada Y, Elbers C, Peters B, Stewart A, Reilly MM, Thorand B, Yusuf S, Engert JC, Assimes TL, Kooner J, Danesh J, Watkins H, Samani NJ, Collins R, Peto R for the MTHFR Studies Collaborative Group.
    Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.
    PLoS Med 2012;9:e1001177.

  64. Hiramatsu M, Oguri M, Kato K, Horibe H, Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Shin D-J, Lee JH, Jang Y, Yamada Y.
    Synergistic effects of genetic variants of APOA5 and BTN2A1 on dyslipidemia or metabolic syndrome in East Asian populations.
    Int J Mol Med 2012;30:185-192.

  65. Chang J, Oikawa S, Ichihara G, Nanpei Y, Hotta Y, Yamada Y, Tada-Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Ichihara S.
    Altered gene and protein expression in liver of the obese spontaneously hypertensive/NDmcr-cp rat.
    Nutr Metab 2012;9:87.

  66. Yamada Y.
    Molecular genetics of stroke.
    In Dhavendra Kumar, ed. Colloquium Series on Genomic and Molecular Medicine, p1-69, Morgan & Claypool Life Sciences, San Rafael, California, 2012.

    67. -2011-
  67. Pereira TV, Mingroni-Netto RC, Yamada Y.
    ADRB2 and LEPR gene polymorphisms: synergistic effects on the risk of obesity in Japanese.
    Obesity 2011;19:1523-1527.

  68. Yamada Y, Nishida T, Ichihara S, Sawabe M, Fuku N, Nishigaki Y, Aoyagi Y, Tanaka M, Fujiwara Y, Yoshida H, Shinkai S, Satoh K, Kato K, Fujimaki T, Yokoi K, Oguri M, Yoshida T, Watanabe S, Nozawa Y, Hasegawa A, Kojima T, Han B-G, Ahn Y, Lee M, Shin D-J, Lee JH, Jang Y.
    Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations.
    Atherosclerosis 2011;215:145-152.

  69. Yoshida T, Kato K, Oguri M, Horibe H, Kawamiya T, Yokoi K, Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Yamada Y.
    Association of a polymorphism of BTN2A1 with chronic kidney disease in Japanese individuals with or without hypertension or diabetes mellitus.
    Exp Ther Med 2011;2:325-331.

  70. Yoshida T, Kato K, Oguri M, Horibe H, Kawamiya T, Yokoi K, Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Yamada Y.
    Association of polymorphisms of BTN2A1 and ILF3 with myocardial infarction in Japanese individuals with different lipid profiles.
    Mol Med Rep 2011;4:511-518.

  71. Yoshida T, Kato K, Oguri M, Horibe H, Kawamiya T, Yokoi K, Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Yamada Y.
    Association of polymorphisms of BTN2A1 and ILF3 with myocardial infarction in Japanese individuals with or without hypertension, diabetes mellitus, or chronic kidney disease.
    Int J Mol Med 2011;27:745-752.

  72. Nishida T, Yamada Y.
    The nucleolar SUMO-specific protease SMT3IP1/SENP3 attenuates Mdm2-mediated p53 ubiquitination and degradation.
    Biochem Biophys Res Commun 2011;406:285-291.

  73. Horibe H, Kato K, Oguri M, Yoshida T, Fujimaki T, Kawamiya T, Yokoi K, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Murohara T, Yamada Y.
    Association of a polymorphism of BTN2A1 with hypertension in Japanese individuals.
    Am J Hypertens 2011;24:924-929.

  74. Hiramatsu M, Oguri M, Kato K, Yoshida T, Fujimaki T, Horibe H, Yokoi K, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Murohara T, Yamada Y.
    Association of a polymorphism of BTN2A1 with type 2 diabetes mellitus in Japanese individuals.
    Diabetic Med 2011;28:1381-1387.

  75. Yoshida T, Kato K, Horibe H, Oguri M, Fukuda M, Satoh K, Aoyagi Y, Shinkai S, Nozawa Y, Yamada Y.
    Association of a genetic variant of BTN2A1 with chronic kidney disease in Japanese individuals.
    Nephrology 2011;16:642-648.

  76. Fujimaki T, Kato K, Oguri M, Yohida T, Horibe H, Yokoi K, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Shin D-J, Lee JH, Jang Y, Yamada Y.
    Association of a polymorphism of BTN2A1 with dyslipidemia in East Asian populations.
    Exp Ther Med 2011;2:745-749.

  77. Oguri M, Kato K, Yoshida T, Fujimaki T, Horibe H, Yokoi K, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Shin D-J, Lee JH, Jang Y, Yamada Y.
    Association of a genetic variant of BTN2A1 with metabolic syndrome in East Asian populations.
    J Med Genet 2011;48:787-792.

  78. Yamada Y, Ichihara S, Nishida T.
    Genome-wide association studies of coronary heart disease.
    In Ion Tintoiu, Alain Rivard, Florina Pinte, Cristian Gabriel, Evelyn Regar, eds.
    Coronary stent restenosis. Bucharest: Romania Medical Academy Press; P329-340, 2011.

  79. Yamada Y. Author Interviews from Hemodialysis.com. Dr. Yamada: Association of a genetic variant of BTN2A1 with chronic kidney disease in Japanese individuals.
    Hemodialysis.com (http://www.hemodialysis.com/), 2011.

    80. -2010-
  80. Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Association of genetic variants with chronic kidney disease in Japanese individuals with or without hypertension or diabetes mellitus.
    Exp Ther Med 2010;1:137-145.

  81. Oguri M, Kato K, Yokoi K, Yoshida T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Association of a polymorphism of SDK1 with hypertension in Japanese individuals.
    Am J Hypertens 2010;23:70-77.

  82. Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Association of genetic variants with myocardial infarction in Japanese individuals with different lipid profiles.
    Int J Mol Med 2010;25:607-616.

  83. Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Association of genetic variants with ischemic stroke in Japanese individuals with or without metabolic syndrome.
    Int J Mol Med 2010;25:281-286.

  84. Fujimaki T, Kato K, Yokoi K, Yoshida T, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Kimura G, Yamada Y.
    Association of genetic variants in SEMA3F, CLEC16A, LAMA3, and PCSK2 with myocardial infarction in Japanese individuals.
    Atherosclerosis 2010;210:468-473.

  85. Oguri M, Nagahiro T, Kamiya H, Ohno M, Kato K, Yokoi K, Yoshida T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Association of a polymorphism of ROR2 and ischemic stroke in Japanese individuals with chronic kidney disease.
    Exp Ther Med 2010;1:377-384.

  86. Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Association of genetic variants with hemorrhagic stroke in Japanese individuals.
    Int J Mol Med 2010;25:649-656.

  87. Fujimaki T, Kato K, Yokoi K, Yoshida T, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Genetic risk for myocardial infarction in Japanese individuals with or without chronic kidney disease.
    Int J Mol Med 2010;25:743-749.

  88. Ichihara S, Yamada Y, Liu F, Murohara T, Itoh K, Yamamoto M, Ichihara G.
    Ablation of Nrf2 resulted in the accerelation of ischemia-induced angiogenesis.
    Arterioscler Thromb Vasc Biol 2010;30:1553-1561.

  89. Kawamiya T, Kato K, Horibe H, Yokoi K, Oguri M, Yoshida T, Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Nozawa Y, Murohara T, Yamada Y.
    Association of genetic variants with myocardial infarction in Japanese individuals with or without metabolic syndrome.
    Exp Ther Med 2010;1:969-975.

  90. Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration.
    Triglyceride-mediated pathways and coronary disease: collaborative analysis for 101 studies.
    Lancet 2010;375:1634-1639.

  91. Yamada Y, Ichihara S, Nishida T.
    Stroke.
    In Dhavendra Kumar, Perry Elliot, eds. Clinical Cardiovascular Genetics: Principle and Practice. New York: Oxford University Press; P337-350, 2010.

  92. Yamada Y, Ichihara S, Nishida T. Genetics of coronary artery disease.
    In Dhavendra Kumar, Perry Elliot, eds. Clinical Cardiovascular Genetics: Principle and Practice. New York: Oxford University Press; P315-328, 2010.

  93. Yamada Y.
    Molecular genetics of myocardial infarction.
    Encyclopedia of Life Sciences (http://www.els.net/), 2010.

    94. -2009-
  94. Oguri M, Kato K, Yokoi K, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Yoshida H, Nozawa Y, Yamada Y.
    Association of polymorphisms of THBS2 and HSPA8 with hypertension in Japanese individuals with chronic kidney disease.
    Mol Med Rep 2009;2:205-211.

  95. Yoshida T, Kato K, Fujimaki T, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Tanaka M, Nozawa Y, Yamada Y.
    Association of a polymorphism of apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome.
    Genomics 2009;93:221-226.

  96. Yoshida T, Kato K, Yokoi K, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Suzuki T, Nozawa Y, Yamada Y.
    Association of genetic variants with chronic kidney disease in Japanese individuals with type 2 diabetes mellitus.
    Int J Mol Med 2009;23:529-537.

  97. Yamada Y, Ando F, Shimokata H.
    Association of polymorphisms of SORBS1, GCK, and WISP1 with hypertension in community-dwelling Japanese individuals.
    Hypertens Res 2009;32:325-331.

  98. Fujimaki T, Kato K, Yoshida T, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Tanaka M, Nozawa Y, Kimura G, Yamada Y.
    Association of genetic vriants with myocardial infarction in Japanese individuals with chronic kidney disease.
    Thromb Haemost 2009;101:963-968.

  99. Ichihara S, Yamada Y, Ichihara G, Nakajima T, Gonzalez FJ, Murohara T.
    Ablation of aryl hydrocarbon-induced receptor resulted in attenuation of impairment of ischemia-induced angiogenesis by benzo[a]pyrene.
    Biochem Biophys Res Commun 2009;381:44-49.

  100. Yoshida T, Kato K, Fujimaki T, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Tanaka M, Nozawa Y, Kimura G, Yamada Y.
    Association of genetic variants with chronic kidney disease in Japanese individuals.
    Clin J Am Soc Nephrol 2009;4:883-890.

  101. Oguri M, Kato K, Yokoi K, Itoh T, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Tanaka M, Nozawa Y, Yamada Y.
    Association of genetic variants with myocardial infarction in Japanese individuals with metabolic syndrome.
    Atherosclerosis 2009;206:486-493.

  102. Yoshida T, Kato K, Yokoi K, Watanabe S, Metoki N, Satoh K, Aoyagi Y, Nishigaki Y, Nozawa Y, Yamada Y.
    Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with hypertension.
    Hypertens Res 2009;32:411-418.

  103. Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Nozawa Y, Yamada Y.
    Association of gene polymorphisms with chronic kidney disease in high-risk or low-risk subjects defined by conventional risk factors.
    Int J Mol Med 2009;23:785-792.

  104. Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nishigaki Y, Nozawa Y, Yamada Y.
    Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.
    Int J Mol Med 2009;24:233-246.

  105. Yamada Y, Fuku N, Tanaka M, Aoyagi Y, Sawabe M, Metoki N, Yoshida H, Satoh K, Kato K, Watanabe S, Nozawa Y, Hasegawa A, Kojima T.
    Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study.
    Atherosclerosis 2009;207:144-149.

  106. Oguri M, Kato K, Yokoi K, Yoshida T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Tanaka M, Nozawa Y, Yamada Y.
    Association of a polymorphism of BCHE with ischemic stroke in Japanese individuals with chronic kidney disease.
    Mol Med Rep 2009;2:779-785.

  107. Hinohara K, Nakajima T, Yasunami M, Houda S, Sasaoka T, Yamamoto K, Lee B-S, Shibata H, Tanaka-Takahashi Y, Takahashi M, Arimura T, Sato A, Naruse T, Ban J, Inoko H, Yamada Y, Sawabe M, Park J-E, Izumi T, Kimura A.
    Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease.
    Hum Genet 2009;126:539-547.

  108. Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Association of gene polymorphisms with chronic kidney disease in Japanese individuals.
    Int J Mol Med 2009;24:539-547.

  109. Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.
    Association of genetic variants with myocardial infarction in individuals with or without hypertension or diabetes mellitus.
    Int J Mol Med 2009;24:701-709.

  110. Yamada Y.
    Genome-wide association studies of myocardial infarction.
    International Atherosclerosis Society (http://www.athero/org/), 2009.

    111. -2008-
  111. Yamada Y, Kato K, Yoshida T, Yokoi K, Matsuo H, Watanabe S, Metoki N, Yoshida H, Satoh K, Ichihara S, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Lee W, Nozawa Y.
    Genetic risk for metabolic syndrome: examination of candidate gene polymorphisms related to lipid metabolism in Japanese individuals.
    J Med Genet 2008;45:22-28.

  112. Yamada Y, Kato K, Yoshida T, Yokoi K, Matsuo H, Watanabe S, Ichihara S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y.
    Association of polymorphisms of ABCA1 and ROS1 with hypertension in Japanese individuals.
    Int J Mol Med 2008;21:83-89.

  113. Yamada Y, Kato K, Oguri M, Fujimaki T, Yokoi K, Matsuo H, Watanabe S, Metoki N, Yoshida H, Satoh K, Ichihara S, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y.
    Genetic risk for myocardial infarction determined by polymorphisms of candidate genes in Japanese individuals.
    J Med Genet 2008;45:216-221.

  114. Yamada Y, Metoki N, Yoshida H, Satoh K, Kato K, Hibino T, Yokoi K, Watanabe S, Ichihara S, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y.
    Genetic factors for ischemic and hemorrhagic stroke in Japanese individuals.
    Stroke 2008;39:2211-2218.

  115. Yamada Y, Ando F, Shimokata H.
    Association of genetic variants of MAOA and SH2B1 with bone mineral density in community-dwelling Japanese women.
    Mol Med Rep 2008;1:269-274.

  116. Yamada Y, Ando F, Shimokata H.
    Association of genetic variants of APOA5 and PRKCH with hypertension in community-dwelling Japanese individuals.
    Mol Med Rep 2008;1:407-414.

  117. Pereira T V, Nunes A C F, Rudnicki M, Yamada Y, Pereira A C, Krieger J E.
    Meta-analysis of the association of four angiotensinogen polymorphisms with essential hypertension: a role beyond M235T?
    Hypertension 2008;51:778-783.

  118. Takemura M, Sugimura K, Okumura K, Limsirichaikul S, Suzuki M, Yamada Y, Yoshida S.
    Hyper-phosphorylated retinoblastoma protein suppresses telomere elongation.
    Biosci Biotech Biochem 2008;72;70715-1-6.

  119. Yamada Y, Kato K, Oguri M, Yoshida T, Yokoi K, Watanabe S, Metoki N, Yoshida H, Satoh K, Ichihara S, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y.
    Association of genetic variants with atherothrombotic cerebral infarction among Japanese individuals with metabolic syndrome.
    Int J Mol Med 2008;21:801-808.

  120. Ichihara S, Yamada Y, Kato K, Hibino T, Yokoi K, Matuso H, Kojima T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y.
    Association of a polymorphism of ABCB1 with obesity in Japanese individuals.
    Genomics 2008;91:512-516.

  121. Kato K, Oguri M, Kato N, Hibino T, Yajima K, Yoshida T, Metoki N, Yoshida H, Satoh K, Watanabe S, Yokoi K, Murohara T, Yamada Y.
    Assessment of genetic risk factors for thoracic aortic aneurysm in hypertensive patients.
    Am J Hypertens 2008;21:1023-1027.

  122. Nishida T, Yamada Y.
    SMT3IP1, a nucleolar SUMO-specific protease, deconjugates SUMO-2 from nucleolar and cytoplasmic nucleophosmin.
    Biochem Biophys Res Commun 2008;374:382-387.

  123. Ichihara S, Yamada Y.
    Genetics factors for human obesity.
    Cell Mol Life Sci 2008;65:1086-1098.

  124. Yamada Y, Ichihara S, Nishida T.
    Molecular genetics of myocardial infarction.
    Genomic Med 2008;2:7-22.

  125. Yamada Y, Ichihara S, Nishida T.
    Proinflammatory gene polymorphisms and ischemic stroke.
    Curr Pharm Des 2008;14:3590-3600.

  126. Yamada Y, Ichihara S, Takemura M.
    Human functional genomics and proteomics.
    In: Dhavendra Kumar, David Weatherall, eds. Genomics and Clinical Medicine.
    New York: Oxford University Press; p31-43, 2008.

  127. Yamada Y.
    Genomics of osteoporosis and related phenotypes.
    In Dhavendra Kumar, David Weatherall, eds. Genomics and Clinical Medicine.
    New York: Oxford University Press; p529-543, 2008

  128. Yamada Y.
    The electronic health recored as a primary source of clinical phenotype for genetic epidemiological studies.
    Genomic Med 2008;2:5.

    129. -2007-
  129. Nishigaki Y, Yamada Y, Fuku N, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Yamaguchi S, Nozawa Y, Tanaka M.
    Mitochondrial haplogroup N9b is protective against myocardial infarction in Japanese males.
    Hum Genet 2007;120:827-836.

  130. Nishihama K, Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Hibino T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y.
    Genetic risk for myocardial infarction stratified by sex or the presence or absence of conventional risk factors.
    Int J Mol Med 2007;19:129-141.

  131. Tanaka M, Fuku N, Nishigaki Y, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Ito M, Nozawa Y, Yamada Y.
    Women with mitochondrial haplogroup N9a are protected against metabolic syndrome.
    Diabetes 2007;56:518-521.

  132. Yamada Y, Kato K, Hibino T, Yokoi K, Matsuo H, Segawa T, Watanabe S, Ichihara S, Yoshida H, Satoh K, Nozawa Y.
    Prediction of genetic risk for metabolic syndrome.
    Atherosclerosis 2007;191:298-304.

  133. Nishigaki Y, Yamada Y, Fuku N, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Yamaguchi S, Nozawa Y, Tanaka M.
    Mitochondrial haplogroup A is a genetic risk factor for atherothrombotic cerebral infarction in Japanese females.
    Mitochondrion 2007;7:72-79.

  134. Oguri M, Kato K, Hibino T, Yokoi K, Segawa T, Matsuo H, Watanabe S, Nozawa Y, Murohara T, Yamada Y.
    Genetic risk for restenosis after coronary stenting.
    Atherosclerosis 2007;194:e172-e178.

  135. Yamaguchi S, Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y.
    Gender differences in the association of gene polymorphisms with type 2 diabetes mellitus.
    Int J Mol Med 2007;19:631-637.

  136. Kato K, Oguri M, Hibino T, Yajima K, Yoshida H, Satoh K, Matsuo H, Segawa T, Watanabe S, Nozawa Y, Yokoi K, Yamada Y.
    Genetic factors for lone atrial fibrillation.
    Int J Mol Med 2007;19:933-939.

  137. Fuku N, Park KS, Yamada Y, Nishigaki Y, Cho YM, Matsuo H, Segawa T, Watanabe S, Kato K, Yokoi K, Nozawa Y, Lee HK, Masashi Tanaka M.
    Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians.
    Am J Hum Genet 2007;80:407-415.

  138. Ichihara S, Yamada Y, Ichihara G, Ping L, Kondo T, Gonzales FJ, Murohara T.
    A role of aryl hydrocardon receptor in the regulation of angiogenesis.
    Arterioscler Thromb Vasc Biol 2007; 27:1297-1304.

  139. Yamada Y, Ando F, Shimokata H.
    Association of gene polymorphisms with blood pressure and the prevalence of hypertension in community-dwelling Japanese individuals.
    Int J Mol Med 2007;19:675-683.

  140. Yamada Y, Ando F, Shimokata H.
    Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men.
    Int J Mol Med 2007;19:791-801.

  141. Nishida T, Terashima M, Fukami K, Yamada Y.
    PIASy regulates ubiquitination-dependent proteosomal degradation of Ets-1.
    Biochem J 2007;405:481-488.

  142. Ichihara S, Yamada Y, Kawai Y, Osawa T, Furuhashi K, Duan Z, Ichihara G.
    Roles of oxidative stress and Akt signaling in doxorubicin cardiotoxicity.
    Biochem Biophys Res Commun 2007;359:27-33.

  143. Pereira TV, Rudnicki M, Cheung BMY, Baum L, Yamada Y, Oliveira PSL, Pereira AC, Krieger JE.
    Three endothelial nitric oxide (NOS3) gene polymorphisms in 19,917 hypertensives and 20,496 normotensives: meta-analysis of 53 studies reveals evidence for publication bias.
    J Hypertens 2007;25:1763-1774.

  144. Yoshida T, Yajima K, Hibino T, Kato K, Matsuo H, Segawa T, Watanabe S, Oguri M, Yokoi K, Nozawa Y, Kimura G, Yamada Y.
    Association of gene polymorphisms with myocardial infarction in individuals with different lipid profiles.
    Int J Mol Med 2007;20:581-590.

  145. Nishida T, Terashima M, Fukami K, Yamada Y.
    Repression of E1AF transcription activity by sumoylation and PIASy.
    Biochem Biophys Res Commun 2007;360:226-232.

  146. Oguri M, Kato K, Hibino T, Yokoi K, Segawa T, Matsuo H, Watanabe S, Nozawa Y, Murohara T, Yamada Y.
    Identification of a polymorphism of UCP3 associated with recurrent in-stent restenosis of coronary arteries.
    Int J Mol Med 2007;20:533-538.

  147. Yamada Y, Matsuo H, Warita S, Watanabe S, Kato K, Oguri M, Yokoi K, Metoki N, Yoshida H, Satoh K, Ichihara S, Aoyagi Y, Yasunaga A, Park H, Tanaka M, Nozawa Y.
    Prediction of genetic risk for dyslipidemia.
    Genomics 2007;90:551-558.

  148. Yamada Y, Matsuo H, Watanabe S, Kato K, Hibino T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y.
    Association of a polymorphism of CYP3A4 with type 2 diabetes mellitus.
    Int J Mol Med 2007;20:703-707.

    149. -2006-
  149. Yamada Y, Ando F, Shimokata H.
    Association of a microsomal triglyceride transfer protein gene polymorphism with blood pressure in Japanese women.
    Int J Mol Med 2006;17:83-88.

  150. Ichihara S, Noda A, Nagata K, Obata K, Xu J, Ichihara G, Oikawa S, Kawanishi S, Yamada Y, Yokota M.
    Pravastatin increases survival and suppresses an increase in myocardial MMP activity in a rat model of heart failure.
    Cardiovasc Res 2006;69:726-735.

  151. Yamada Y, Banno Y, Yoshida H, Kikuchi R, Akao Y, Murate T, Nozawa Y.
    Catalytic inactivation of human phospholipase D2 by a naturally occurring Gly901Asp mutation.
    Arch Med Res 2006;37:696-699.

  152. Yamada Y, Ando F, Shimokata H.
    Association of polymorphisms in forkhead box C2 and perilipin genes with bone mineral density in community-dwelling Japanese individuals.
    Int J Mol Med 2006;18:119-127.

  153. Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Hibino T, Yokoi K, Yoshida H, Metoki N, Satoh K, Ichihara S, Nozawa Y.
    Assessment of genetic component for hypertension.
    Am J Hypertens 2006;19:1158-1165.

  154. Yamada Y, Metoki N, Yoshida H, Satoh K, Ichihara S, Kato K, Kameyama T, Yokoi K, Matsuo H, Segawa T, Watanabe S, Nozawa Y.
    Genetic risk for ischemic and hemorrhagic stroke.
    Arterioscler Thromb Vasc Biol 2006;26:1920-1925.

  155. Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Kameyama T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y.
    Assessment of the genetic factors for type 2 diabetes mellitus.
    Int J Mol Med 2006;18:299-308.

  156. Ichihara S, Obata K, Yamada Y, Nagata K, Noda A, Ichihara G, Yamada A, Kato T, Izawa H, Murohara T, Yokota M.
    Attenuation of cardiac dysfunction by a PPAR-ƒΏ agonist is associated with down-regulation of redox-regulated transcription factors.
    J Mol Cell Cardiol 2006;41:318-329.

  157. Takemura M, Yoshida S, Akiyama T, Kitagawa M, Yamada Y.
    Role of the second-largest subunit of DNA polymerase ƒΏ in the interaction between the catalytic subunit and hyperphosphorylated retinoblastoma protein in late S phase.
    Biochim Biophys Acta - Proteins Proteom 2006;1764:1447-1453.

  158. Yamada Y, Matsuo H, Segawa T, Watanabe S, Kato K, Hibino T, Yokoi K, Ichihara S, Metoki N, Yoshida H, Satoh K, Nozawa Y.
    Assessment of genetic risk for myocardial infarction.
    Thromb Haemost 2006;96:220-227.

  159. Ichihara S, Yamada Y, Ichihara G, Kanazawa H, Hashimoto K, Kato Y, Matsushita A, Oikawa S, Yokota M, Iwase M.
    Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal mode of dilated cardiomyopathy.
    Biochem Biophys Res Commun 2006;350:105-113.

  160. Yamaguchi S, Yamada Y, Metoki N, Yoshida H, Satoh K, Ichihara S, Kato K, Kameyama T, Yokoi K, Matsuo H, Segawa T, Watanabe S, Nozawa Y.
    Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis.
    Int J Mol Med 2006;18:871-883.

  161. Yamada Y, Kato K, Kameyama T, Yokoi K, Matsuo H, Segawa T, Watanabe S, Ichihara S, Yoshida H, Satoh K, Nozawa Y.
    Genetic factors for obesity.
    Int J Mol Med 2006;18:843-851.

  162. Yamada Y.
    Identification of genetic factors and development of genetic risk diagnosis systems for cardiovascular diseases and stroke.
    Circ J 2006;70:1240-1248.

    163. -2005-
  163. Yamada Y, Ando F, Niino N, Shimokata H.
    Association of polymorphisms of the androgen receptor and klotho genes with bone mineral density in Japanese women.
    J Mol Med 2005;83:50-57.

  164. Yamada Y, Ando F, Niino N, Shimokata H.
    Association of a -1997G¨T polymorphism of collagen IƒΏ1 gene with bone mineral density.
    Hum Biol 2005;77:27-36.

  165. Yamada Y, Ando F, Shimokata H.
    Association of polymorphisms in CYP17, MTP, and VLDLR with bone mineral density in community-dwelling Japanese women and men.
    Genomics 2005;86:76-85.

  166. Obata K, Nagata K, Iwase M, Odashima M, Nagasaka T, Yamada Y, Yokota M.
    Overexpression of calmodulin induces cardiac hypertrophy by a calcineurin-dependent pathway.
    Biochem Biophys Res Commun 2005;338:1299-1305.

  167. Yamada Y.
    Genetic Disorders of the Indian Subcontinent.
    J Med Genet 2005;43;288.

    168. -2004-
  168. Shimokata K, Yamada Y, Kondo T, Izawa H, Nagata K, Murohara T, Ohno M, Yokota M.
    Association of gene polymorphisms with coronary artery disease in individuals with or without nonfamilial hypercholesterolemia.
    Atherosclerosis 2004;172:167-173.

  169. Yamada Y, Ando F, Niino N, Shimokata H.
    Association of a polymorphism of the matrix metalloproteinase-9 gene with bone mineral density in Japanese men.
    Metabolism 2004;53:135-137.

  170. Yamada Y, Ichihara S, Izawa H, Tanaka M, Yokota M.
    Genetic risk for coronary artery disease in individuals with or without type 2 diabetes.
    Mol Genet Metab 2004;81:282-290.

  171. Murase Y, Yamada Y, Hirashiki A, Ichihara S, Kanda H, Watarai M, Takatsu F, Murohara T, Yokota M.
    Genetic risk and gene-environmental interaction in coronary artery spasm in Japanese men and women.
    Eur Heart J 2004;25:970-977.

  172. Horibe H, Yamada Y, Ichihara S, Watarai M, Yanase M, Takemoto K, Shimizu S, Izawa H, Takatsu F, Yokota M.
    Genetic risk for restenosis after coronary balloon angioplasty.
    Atherosclerosis 2004;174:181-187.

  173. Takagi K, Yamada Y, Gong JS, Sone T, Yokota M, Tanaka M.
    Association of a 5178C¨A (Leu237Met) polymorphism in the mitochondrial DNA with a low prevalence of myocardial infarction in Japanese individuals.
    Atherosclerosis 2004;175:281-286.

  174. Yamada A, Ichihara S, Murase Y, Kato T, Izawa H, Murohara T, Yamada Y, Yokota M.
    Lack of association of polymorphisms of the lymphotoxin ƒΏ gene with myocardial infarction in Japanese.
    J Mol Med 2004;82:477-483.

  175. Tanaka M, Cabrera VM, Gonzalez AM, Larruga JM, Takeyasu T, Fuku N, Guo LJ, Hirose R, Fujita Y, Kurata M, Shinoda K, Umetsu K, Yamada Y, Oshida Y, Sato Y, Hattori N, Mizuno Y, Arai Y, Hirose N, Ohta S, Ogawa O, Tanaka Y, Kawamori R, Shamoto-Nagai M, Maruyama W, Shimokata H, Suzuki R, Shimodaira H.
    Mitochondrial Genome Variation in Eastern Asia and the peopling of Japan.
    Genome Res 2004;14:1832-1850.

  176. Hirashiki A, Yamada Y, Yokota M.
    Association of gene polymorphisms with coronary artery disease.
    J Am Coll Cardiol 2004;44:209-210.

    177. -2003-
  177. Yamada Y, Hamajima N, Kato T, Iwata H, Yamamura Y, Shinoda M, Suyama M, Mitsudomi T, Tajima K, Kusakabe S, Yoshida H, Banno Y, Akao Y, Tanaka M, Nozawa Y.
    Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancer.
    J Mol Med 2003;81:126-131.

  178. Noto H, Hara M, Karasawa K, Iso-o N, Satoh H, Togo M, Hashimoto Y, Yamada Y, Kosaka T, Kawamura M, Kimura S, Tsukamoto K.
    Human plasma platelet-activating factor acetylhydrolase binds to all the murine lipoproteins, conferring protection against oxidative stress.
    Arterioscler Thromb Vasc Biol 2003;23:829-835.

  179. Izawa H, Yamada Y, Okada T, Tanaka M, Hirayama H, Yokota M.
    Prediction of genetic risk for hypertension.
    Hypertension 2003;41:1035-1040.

  180. Yamada Y, Ando F, Niino N, Shimokata H.
    Association of polymorphisms in the interleukin-6, osteocalcin, and vitamin D receptor genes, alone or in combination, with bone mineral density in community-dwelling Japanese women and men.
    J Clin Endocrinol Metab 2003;88:3372-3378.

  181. Yamada Y, Ando F, Niino N, Shimokata H.
    Association of polymorphisms of the osteoprotegerin gene with bone mineral density in Japanese women but not men.
    Mol Genet Metab 2003;80:344-349.

  182. Hirashiki A, Yamada Y, Murase Y, Suzuki Y, Kataoka H, Morimoto Y, Tajika T, Kanda H, Ishihara H, Yokota M.
    Association of gene polymorphisms with coronary artery disease in low- or high-risk subjects defined by conventional risk factors.
    J Am Coll Cardiol 2003;42:1429-1437.

  183. Yamada Y, Ando F, Niino N, Miki T, Shimokata H.
    Association of polymorphisms of paraoxonase 1 and 2 genes, alone or in combination, with bone mineral density in community-dwelling Japanese.
    J Hum Genet 2003;48:469-475.

  184. Yamada Y, Ando F, Niino N, Shimokata H.
    Association of a polymorphism of the dopamine receptor D4 gene with bone mineral density in Japanese men.
    J Hum Genet 2003;48:629-633.

  185. Yamada Y.
    Molecular genetics and epidemiology of osteoporosis.
    Curr Pharmacogenomics 2003;1:139-149.

  186. Yamada Y, Yokota M.
    Risk of Myocardial infarction and polymorphisms in candidate genes.
    N Engl J Med 2003;348:1176-1177.

    187. -2002-
  187. Fuku N, Oshida Y, Takeyasu T, Gao LJ, Kurata M, Yamada Y, Sato Y, Tanaka M.
    Mitochondrial ATPase subunit 6 and cytochrome b gene polymorphisms in young obese adults.
    Biochem Biophys Res Commun 2002;290:1199-1205.

  188. Obata K, Koide M, Nagata K, Iio A, Yazawa S, Ono T, Sasaki S, Yamada Y, Tuan RS, Yokota M.
    Effects of FK506 and rapamycin on formation of the neural tube in chick embryos.
    Anim Sci J 2002;73:229-234.

  189. Yamada Y, Ando F, Niino N, Shimokata H.
    Association of a polymorphism of the CC chemokine receptor-2 gene with bone mineral density.
    Genomics 2002;80:8-12.

  190. Yamada Y, Ando F, Niino N, Shimokata H.
    Association of a polymorphism of the matrix metalloproteinase-1 gene with bone mineral density.
    Matrix Biol 2002;21:389-392.

  191. Yamada Y, Fujisawa M, Ando F, Niino N, Tanaka M, Shimokata H.
    Association of a polymorphism of the transforming growth factor-ƒΐ1 gene with blood pressure in Japanese individuals.
    J Hum Genet 2002;47:243-248.

  192. Yamada Y, Ando F, Niino N, Ohta S, Shimokata H.
    Association of polymorphisms of the estrogen receptor ƒΏ gene with bone mineral density of the femoral neck in elderly Japanese women.
    J Mol Med 2002;80:452-460.

  193. Hase M, Yokota M, Tanaka M, Yamada Y.
    Reduction in the extent of atherosclerosis in apolipoprotein E-deficient mice induced by electroporation-mediated transfer of the human plasma platelet-activating factor acetylhydrolase gene into skeletal muscle.
    Prostaglandins Other Lipid Mediat 2002;70:107-118.

  194. Tanaka M, Borgeld HJ, Zhang J, Gong JS, Yoneda M, Maruyama W, Naoi M, Ibi T, Sahashi K, Shamoto M, Fuku N, Kurata M, Yamada Y, Nishizawa K, Akao Y, Ohishi N, Miyabayashi S, Umemoto H, Muramatsu T, Furukawa K, Kikuchi A, Nakano I, Ozawa K, Yagi K.
    Gene therapy for mitochondrial disease by delivering restriction endonusclease SmaI into mitchondria.
    J Biomed Sci 2002;9:534-541.

  195. Nagata K, Somura F, Obata K, Odashima M, Izawa H, Ichihara S, Nagasaka T, Iw ase M, Yamada Y, Nakashima N, Yokota M.
    AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats.
    Hypertension 2002;40:168-174.

  196. Tanaka M, Fuku N, Takeyasu T, Guo LJ, Hirose R, Kurata M, Borgeld HJ, Yamada Y, Maruyama W, Arai Y, Hirose N, Oshida Y, Sato Y, Hattori N, Mizuno Y, Iwata S, Yagi K.
    Golden mean to longevity: rareness of mitochondrial cytochrome b variants in centenarians but not in patients with Parkinsonfs disease.
    J Neurosci Res 2002;70:347-355.

  197. Uchigata Y, Okada T, Gong JS, Yamada Y, Iwamoto Y, Tanaka M.
    A mitochondrial genotype associated with the development of autoimmune-related type 1 diabetes.
    Diabetes Care 2002;25:2106.

  198. Yamada Y, Izawa H, Ichihara S, Takatsu F, Ishihara H, Hirayama H, Sone T, Tanaka M, Yokota M.
    Prediction of the risk of myocardial infarction from polymorphisms in candidate genes.
    N Engl J Med 2002;347:1916-1923.

    199. -2001-
  199. Takemura M, Harada A, Mizuno M, Yano K, Yamada Y.
    Relation between osteoprotegerin/osteoclestogenesis inhibitory factor concentration in synovial fluid and disease severity in individuals with osteoarthritis of the knee.
    Metabolism 2001;50:1-2.

  200. Yamada Y, Ando F, Niino N, Shimokata H.
    Transforming growth factor-ƒΐ1 gene polymorphism and bone mineral density.
    JAMA 2001;285:167-168.

  201. Yamada Y, Miyauchi A, Takagi Y, Tanaka M, Mizuno M, Harada A.
    Association of the C-509¨T polymorphism, alone or in combination with the T869¨C polymorphism, of the transforming growth factor-ƒΐ1 gene with bone mineral density and genetic susceptibility to osteoporosis in Japanese women.
    J Mol Med 2001;79:149-156.

  202. Matsunaga H, Tanaka Y, Tanaka M, Gong JS, Zhang J, Nomiyama T, Ogawa O, Ogihara T, Yamada Y, Yagi K, Kawamori R.
    Antiatherogenic mitochondrial genotype in patients with type 2 diabetes.
    Diabetes Care 2001;24:500-503.

  203. Obata K, Koide M, Nagata K, Iio A, Yazawa S, Ono T, Yamada Y, Tuan RS, Yokota M.
    Role of FK506-binding protein 12 in development of the chick embryonic heart.
    Biochem Biophys Res Commun 2001;283:613-620.

  204. Kamiya M, Harada A, Mizuno M, Iwata H, Yamada Y.
    Association between a polymorphism of the transforming growth factor-ƒΐ1 gene and genetic susceptibility to ossification of the posterior longitudinal ligament in Japanese patients.
    Spine 2001;26:1264-1266.

  205. Yamada Y, Ichihara S, Izawa H, Yokota M.
    Association of a G994¨T (Val279¨Phe) polymorphism of the plasma platelet-activating factor acetylhydrolase gene with myocardial damage in Japanese patients with nonfamilial hypertrophic cardiomyopathy.
    J Hum Genet 2001;46:436-441.

  206. Somura F, Izawa H, Iwase M, Takeichi Y, Ishiki R, Nishizawa T, Noda A, Nagata K, Yamada Y, Yokota M.
    Reduced myocardial sarcoplasmic reticulum Ca2+-ATPase mRNA expression and biphasic force-frequency relation in patients with hypertrophic cardiomyopathy.
    Circulation 2001;104:658-663.

  207. Yamada Y.
    Association of polymorphisms of the transforming growth factor-ƒΐ1 gene with genetic susceptibility to osteoporosis.
    Pharmacogenetics (Pharmacogenet Genomics) 2001;11:765-771.

    208. -2000-
  208. Yamada Y, Okuizumi H, Miyauchi A, Takagi Y, Ikeda K, Harada A.
    Association of transforming growth factor ƒΐ1 genotype with spinal osteophytosis in Japanese women.
    Arthritis Rheum 2000;43:452-460.

  209. Yamada Y, Harada A, Hosoi T, Miyauchi A, Ikeda K, Ohta H, Shiraki M.
    Association of transforming growth factorƒΐ1 genotype with therapeutic response to active vitamin D for postmenopausal osteoporosis.
    J Bone Miner Res 2000;15:415-420.

  210. Shimokata H, Yamada Y, Nakagawa M, Okubo R, Saido T, Funakoshi A, Miyasaka K, Ohta S, Tsujimoto G, Tanaka M, Ando F, Niino N.
    Distribution of geriatric disease-related genotypes in the National Institute for Longevity Sciences, longitudinal study of aging (NILS-LSA).
    J Epidemiol 2000;10:S46-S55.

  211. Yamada Y, Yoshida H, Ichihara S, Imaizumi T, Satoh K, Yokota M.
    Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population.
    Atherosclerosis 2000;150:209-216.

  212. Yokota M, Ichihara S, Lin TL, Nakashima N, Yamada Y.
    Association of a T29¨C polymorphism of the transforming growth factor-ƒΐ1 gene with genetic susceptibility to myocardial infarction in Japanese.
    Circulation 2000;101:2783-2787.

  213. Kanematsu M, Sato T, Takai H, Watanabe K, Ikeda K, Yamada Y.
    Prostaglandin E2 induces expression of receptor activator of nuclear factor-ƒΘB ligand/osteoprotegerin ligand on pre-B cells: implications for accelerated osteoclastogenesis in estrogen deficiency.
    J Bone Miner Res 2000;15:1321-1329.

  214. Lin TL, Ichihara S, Yamada Y, Nagasaka T, Ishihara H, Nakashima N, Yokota M.
    Phenotypic variation of familial hypertrophic cardiomyopathy caused by the Phe110¨Ile mutation in cardiac troponin T.
    Cardiology 2000;93:155-162.

  215. Yamada Y, Miyauchi A, Takagi Y, Nakauchi K, Miki N, Mizuno M, Harada A.
    Association of a polymorphism of the transforming factor beta-1 gene with prevalent vertebral fractures in Japanese women.
    Am J Med 2000;109:244-247.

  216. Yamada Y.
    Association of a Leu10¨Pro polymorphism of the transforming growth factor-ƒΐ1 with genetic susceptibility to osteoporosis and spinal osteoarthritis.
    Mech Ageing Dev 2000;116:113-123.

  217. Tanaka M, Gong JS, Zhang J, Yamada Y, Borgeld HJ, Yagi K.
    Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis.
    Mech Ageing Dev 2000;116:65-76.

    218. -1999-
  218. Inagaki M, Yokota M, Izawa H, Ishiki R, Nagata K, Iwase M, Yamada Y, Koide M, Sobue T.
    Impaired force-frequency relations in patients with hypertensive left ventricular hypertrophy: a possible physiological marker of the transition from physiologic to pathologic hypertrophy.
    Circulation 1999;99:1822-1830.

  219. Yano K, Tsuda E, Washida N, Kobayashi F, Goto M, Satake T, Harada A, Ikeda K, Higashio K, Yamada Y.
    Immunological characterization of circulating osteoclastogenesis inhibitory factor: increased serum concentrations in postmenopausal women with osteoporosi s.
    J Bone Miner Res 1999;14:518-527.

  220. Yamada Y, Hosoi T, Makimoto F, Tanaka H, Seino Y, Ikeda K.
    Transforming growth factor beta-1 gene polymorphism and bone mineral density in Japanese adolescents.
    Am J Med 1999;106:477-479.

  221. Ichihara S, Yamada Y, Yokota M.
    Familial dilated cardiomyopathy.
    Circulation 1999;100:e87.

    222. -1998-
  222. Ichihara S, Yamada Y, Fujimura T, Nakashima N, Yokota M.
    Association of a polymorphism of the endothelial constitutive nitric oxide synthase gene with myocardial infarction in Japanese population.
    Am J Cardiol 1998;81:83-86.

  223. Yamada Y, Ichihara S, Fujimura T, Yokota M.
    Identification of the G994¨T missense mutation in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men.
    Metabolism 1998;47:177-181.

  224. Kameda T, Mano H, Yamada Y, Takai H, Amizuka N, Kobori M, Izumi N, Kawashima H, Ozawa H, Ikeda K, Kameda A, Hakeda Y, Kumegawa M.
    Calcium-sensing receptor in mature osteoclasts, which are bone resorbing cells.
    Biochem Biophys Res Commun 1998;245:419-422.

  225. Yamada Y, Miyauchi A, Goto J, Takagi Y, Okuizumi Y, Kanematsu M, Hase M, Takai H, Harada A, Ikeda K.
    Association of a polymorphism of the transforming growth factor-ƒΐ1 gene with genetic susceptibility to osteoporosis in postmenopausal Japanese women.
    J Bone Miner Res 1998;13:1569-1576.

  226. Takai H, Kanematsu M, Yano K, Tsuda E, Higashio K, Watanabe K, Ikeda K, Yamada Y.
    Transforming growth factor-ƒΐ stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells.
    J Biol Chem 1998;273:27091-27096.

  227. Ichihara S, Yamada Y, Yokota M. Association of a G994¨T missense mutation in the plasma platelet-activating factor acetylhydrolase gene with genetic susceptibility to nonfamilial dilated cardiomyopathy in Japanese.
    Circulation 1998;98:1881-1885.

  228. Yamada Y, Yokota M.
    Roles of plasma platelet-activating factor acetylhydrolase in allergic, inflammatory, and atherosclerotic diseases.
    Jpn Circ J (Circ J) 1998;62:328-335.

  229. Kanematsu M, Takai H, Yamada Y.
    Actions of nitric oxide in the regulation of osteoclasts and osteoblasts.
    Curr Opin Orthop 1998;9;V:11-16.

    230. -1997-
  230. Yamada Y, Yokota M.
    Effects of protein kinase C activation and inhibition on endothelin-1 release from human aortic and pulmonary artery endothelial cells: comparison with effects on bovine endothelin-1 and human prostaglandin I2 release.
    Am J Hypertens 1997;10:32-42.

  231. Kimura M, Yokota M, Fujimura T, Kato S, Hirayama H, Tsunekawa A, Inagaki H, Maeda M, Ogawa S, Nakashima N, Yamada Y.
    Association of a deletion polymorphism of the angiotensin-converting enzyme gene with left ventricular hypertrophy in Japanese women with essential hypertension: multicenter study of 1919 subjects.
    Cardiology 1997;88:309-314.

  232. Yamada Y, Goto J, Yokata M.
    Brain natriuretic peptide is a sensitive indicator of impaired left-ventricular function in elderly patients with cardiovascular disease.
    Cardiology 1997;88:401-407.

  233. Yamada Y, Yokota M.
    Loss of activity of plasma platelet-activating factor acetylhydrolase due to a novel Gln281¨Arg mutation.
    Biochem Biophys Res Commun 1997;236:772-775.

  234. Yamada Y, Ichihara S, Fujimura T, Yokota M.
    Lack of association of polymorphisms of the angiotensin converting enzyme and angiotensinogen genes with nonfamilial hypertrophic or dilated cardiomyopathy.
    Am J Hypertens 1997;10:921-928.

  235. Ichihara S, Yokota M, Fujimura T, Kato S, Hirayama H, Tsunekawa A, Inagaki H, Takatsu F, Nakashima N, Yamada Y.
    Lack of association between variants of the angiotensinogen gene and coronary artery disease in middle-aged Japanese men.
    Am Heart J 1997;134:260-265.

  236. Kanematsu M, Ikeda K, Yamada Y.
    Interaction between nitric oxide synthase and cyclooxygenase pathways in osteoblastic MC3T3-E1 cells.
    J Bone Miner Res 1997;12:1789-1796.

  237. Fujimura T, Yokota M, Kato S, Hirayama H, Tsunekawa A, Inagaki H, Takatsu F, Nakashima N, Yamada Y.
    Lack of association of angiotensin converting enzyme gene polymorphism or serum enzyme activity with coronary artery disease in Japanese subjects.
    Am J Hypertens 1997;10:1384-1390.

    238. -1996-
  238. Yamada Y, Yokota M.
    Direct interactions of plasminogen activators with human aortic endothellial cells in vitro: implications for thrombolytic therapy.
    J Cardiovasc Pharmacol 1996;27:629-635.

  239. Yamada Y, Yokota M.
    Enhancement of barrier function of human aortic endothelial cells by activators of protein kinase C.
    Biochem Mol Biol Int 1996;39:69-76.

  240. Yamada Y, Yokota M.
    Production of C-type natriuretic peptide from human aortic endothelial cells induced by activation of protein kinase C.
    Am J Hypertens 1996;9:924-929.

  241. Imaizumi T, Stafforini DM, Yamada Y, Zimmerman GA, McIntyre TM, Prescott SM.
    The fate of platelet-activating factor: PAF acetylhydrolase from plasma and tissues.
    Advances in Lipobiology, Richard Gross, editor, JAI Press, Connecticutt, 1996;1A:141-162.

    242. -1995-
  242. Tjoelker LW, Wilder C, Eberhardt C, Stafforini DM, Dietsch G, Schimpf B, Hooper S, Trong H, Cousens LS, Zimmerman GA, Yamada Y, McIntyre TM, Prescott SM, Gray PA.
    Anti-inflammatory properties of a platelet-activating factor acetylhydrolase.
    Nature 1995;374:549-552.

  243. Noda A, Okada T, Yasuma F, Yamada Y, Nakashima N, Yokota M.
    Effect of aging on cardiac and electroencephalographic arousal in sleep apnea/hypopnea syndrome.
    J Am Geriatr Soc 1995;43:1070-1071.

  244. Imaizumi T, Stafforini DM, Yamada Y, McIntyre TM, Prescott SM, Zimmerman GA.
    Platelet-activating factor: a mediator for clinicians.
    J Intern Med 1995;238:5-20.

    245. -1994-
  245. Yamada Y, Stafforini DM, Imaizumi T, Zimmerman GA, McIntyre TM, Prescott SM.
    Characterization of the platelet-activating factor acetylhydrolase from human plasma by heterologous expression in Xenopus laevis oocytes.
    Proc Natl Acad Sci USA 1994;91:10320-10324.

    246. -1992-
  246. Furumichi T, Yamada Y, Suzuki T, Furui H, Yamauchi K, Saito H.
    Adenosine 3':5'-cyclic monophosphate inhibits in vitro angiogenesis induced by endothelial cell growth factor.
    Jpn Heart J (Int Heart J) 1992;33:373-382.

  247. Suzuki T, Yamauchi K, Yamada Y, Furumichi T, Furui H, Tsuzuki J, Hayashi H, Sotobata I, Saito H.
    Blood coagulability and fibrinolytic activity before and after physical training during the recovery phase of acute myocardial infarction.
    Clin Cardiol 1992;15:358-364.

    248. -1991-
  248. Yamada Y, Furui H, Furumichi T, Yamauchi K, Yokota M, Saito H.
    Possible mechanism of vascular reocclusion after initially successful thrombolysis with recombinant tissue-type plasminogen activator.
    Am Heart J 1991;121:1618-1627.

    249. -1990-
  249. Watabe S, Hayashi H, Yamada Y, Miyaji K, Yabe S, Sotobata I, Iwata A, Suzumura N.
    Application of Karhunen-Loeve expansion to evaluate regional cardiac excitation in body surface potential maps.
    J Electrocardiol 1990;23:33-40.

  250. Yamada Y, Furui H, Furumichi T, Suzuki T, Yamauchi K, Yokota M, Hayashi H, Saito H.
    Inhibitory effects of endothelial cells and calcium channel blockers on platelet aggregation.
    Jpn Heart J (Int Heart J) 1990;31:201-215.

  251. Yamada Y, Furumichi T, Furui H, Yokoi T, Ito T, Yamauchi K, Yokota M, Hayashi H, Saito H.
    Roles of calcium, cyclic nucleotides, and protein kinase C in regulation of endothelial permeability.
    Arteriosclerosis (Arterioscler Thromb Vasc Biol) 1990;10:410-420.

  252. Yamada Y, Yokota M, Furumichi T, Furui H, Yamauchi K, Saito H.
    Protective effects of calcium channel blockers on hydrogen peroxide induced increases in endothelial permeability.
    Cardiovasc Res 1990;24:993-997.

    253. -1989-
  253. Furui H, Yamada Y, Yamauchi K, Hayashi H.
    Effects of oral elastase on lipid metabolism, platelet function, and blood coagulability in patients with diabetes mellitus.
    Clin Ther 1989;11:786-7943.

    254. -1988-
  254. Ishikawa T, Watabe S, Yamada Y, Miyachi K, Sakai Y, Ito A, Sotobata I.
    New diagnostic evidence on the T wave map indicating involved coronary artery in patients with angina pectoris.
    Circulation 1988;77:301-310.

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